Monday 29 December 2014

理化学研究所のスタップ(STAP)細胞研究について報じた日本のジャーナリストに読んでほしい学術論文(英語)

例えば,こんなエッセイに目を通されましたか.以下,ご参考迄にサマリーを引用します.執筆者は,スタンフォードのMeta-Research Innovation CenterのJohn P. A. Ioannidis氏です.
There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice and when more teams are involved in a scientific field in chase of statistical significance. Simulations show that for most study designs and settings, it is more likely for a research claim to be false than true. Moreover, for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias. In this essay, I discuss the implications of these problems for the conduct and interpretation of research.
当該の論文は,こちらから全文無料でダウンロード可能です.

ところで,スタップ細胞を巡る日本のニュースメディアに寄る一連の報道に感じたのは,ホリエモンシンドロームとでも呼べそうな,当時のライブドアの社長だった堀江氏を巡る報道においても見られるものと全く同一の姿勢でした.もちろん,それを世間一般が求めていることも否めませんが.

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